Blood testing could spot cancer early, study says
- On May 8, 2025, researchers published findings indicating that a blood test designed to detect a variety of cancers might identify many cases at stages when treatment is more effective.
- This test arose because current screening covers few cancers reliably, mainly breast, bowel, cervix, and high-risk lung cancers, leaving others undetected early.
- MCED identifies cancer-specific markers, such as tumor-derived DNA fragments, and could enable the earlier detection of roughly one-third to nearly half of cancers at stages I-II that might otherwise be diagnosed at more advanced stages.
- Annual MCED screening was linked to nearly half the number of late-stage cancer cases and a 21% reduction in mortality over five years compared to standard care, while screening every two years delivered smaller yet still significant improvements.
- Researchers concluded that adding MCED annually or biennially to current screening guidelines could improve early detection and reduce deaths, though optimal intervals and real-world compliance remain uncertain.
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33 Articles
DNA remnants in red blood cells enable early detection of cancer
Cytoplasmic DNA emerges as a consequence of genomic instability. However, its potential role in disease diagnosis has yet to be fully explored. Here we analyzed DNA remnants in mature red blood cells (rbcDNA) from both healthy individuals and cancer patients. Our study unveiled distinct genomic profiles in rbcDNA from cancer patients with early-stage solid tumors compared to those of healthy donors. Significant changes in read counts at specific…

Blood Testing Could Catch Cancers Early, Projections Say
Key Takeaways
Many Australians unaware of blood cancer symptoms, research finds
The Leukaemia Foundation says one in 12 people in Australia are at risk of being diagnosed with a blood cancer, but a lack of awareness about symptoms means many cancers go undiagnosed for longer periods.The Foundation says blood cancers are likely to overtake other cancers by 2035.
Annual blood test could detect cancer earlier and save lives
A single blood test, designed to pick up chemical signals indicative of the presence of many different types of cancer, could potentially thwart progression to advanced disease while the malignancy is still at an early stage and amenable to treatment in up to half of cases, suggests a modelling study published in the open access journal BMJ Open.
Blood test for many cancers could thwart progression to late stage in up to half of cases, study suggests
A single blood test, designed to pick up chemical signals indicative of the presence of many different types of cancer, could potentially thwart progression to advanced disease while the malignancy is still at an early stage and amenable to treatment in up to half of cases, suggests a modeling study published in the open access journal BMJ Open.
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