Alcohol Drives Opposite Brain Circuit Changes in Amyloid and Tau Alzheimer's Models

Study reveals complex relationship between alcohol and Alzheimer's disease

Alcohol use has been associated with an increased risk of cognitive decline and dementia. But new research from the Texas A&M University Naresh K. Vashisht College of Medicine at Texas A&M Health suggests the relationship between alcohol and Alzheimer's disease is more complicated than previously thought.

Chronic alcohol use alters Alzheimer's brain circuits differently based on underlying pathology

A new study published in the journal Neuropharmacology suggests that chronic alcohol consumption affects the brain differently depending on the specific underlying characteristics of Alzheimer’s disease. The findings indicate that alcohol alters a key brain circuit responsible for decision-making in opposite ways, depending on whether the brain is burdened by amyloid plaques or tau tangles. This provides evidence that the relationship between al…

Alcohol drives opposite brain circuit changes in amyloid and tau Alzheimer's models

Alcohol use has been associated with an increased risk of cognitive decline and dementia. But new research from Texas A&M University's Naresh K. Vashisht College of Medicine at Texas A&M Health suggests the relationship between alcohol and Alzheimer's disease is more complicated than previously thought. Instead of affecting all Alzheimer's-related brain changes in the same way, alcohol interacted differently with amyloid-beta-related and tau-rel…

Alcohol Alters Brain Flexibility Based on Hidden Dementia Markings

A new study proves alcohol interacts differently with amyloid-beta and tau pathologies in Alzheimer's models.