Skip to main content
See every side of every news story
Published loading...Updated

Akeso Advances "IO 2.0 + ADC 2.0" Strategy with Phase II Initiation of Novel ADCs Combined with Ivonescimab and Cadonilimab

  • Akeso, Inc. received clearance from China's National Medical Products Administration to start Phase II clinical trials for two novel antibody-drug conjugates, AK146D1 and AK138D1, targeting cancer antigens Trop2/Nectin4 and HER3 respectively.
  • The trials will study these antibody-drug conjugates combined with Akeso's bispecific antibodies cadonilimab and ivonescimab, along with other anti-tumor agents, across various advanced solid tumors.
  • Advancing 'IO 2.0 + ADC 2.0' combinations into Phase II marks a key step in Akeso's progress toward next-generation leadership in global oncology.
  • AK146D1 targets Trop2 and Nectin4 antigens found in certain cancers, while AK138D1 targets HER3, which is associated with tumor growth and treatment resistance.
Insights by Ground AI

45 Articles

The Berkshire EagleThe Berkshire Eagle
+43 Reposted by 43 other sources
Center

Akeso Advances "IO 2.0 + ADC 2.0" Strategy with Phase II Initiation of Novel ADCs Combined with Ivonescimab and Cadonilimab

HONG KONG, March 24, 2026 /PRNewswire/ -- Akeso, Inc. (9926.HK) ("Akeso" or the "Company") announced today that it has received clearance from the Center for Drug Evaluation (CDE) of China's National Medical Products Administration (NMPA) to initiate Phase II clinical…

Read Full Article
Think freely.Subscribe and get full access to Ground NewsSubscriptions start at $9.99/yearSubscribe

Bias Distribution

  • 70% of the sources are Center
70% Center

Factuality Info Icon

To view factuality data please Upgrade to Premium

Ownership

Info Icon

To view ownership data please Upgrade to Vantage

PR Newswire broke the news in United States on Wednesday, March 25, 2026.
Too Big Arrow Icon
Sources are mostly out of (0)

Similar News Topics

News
Feed Dots Icon
For You
Search Icon
Search
Blindspot LogoBlindspotLocal