AI screening in brain organoids uncovers two drug candidates for Leigh syndrome
3 Articles
3 Articles
AI screening in brain organoids uncovers two drug candidates for Leigh syndrome
The need for medical treatments for rare diseases such as Leigh syndrome is high. However, low patient numbers make research into treatments difficult. Together with a team from the University of Luxembourg, researchers from Heinrich Heine University Düsseldorf (HHU) and University Hospital Düsseldorf (UKD) have succeeded in utilizing artificial intelligence (AI) to establish a model that enables a better understanding of Leigh syndrome. In the …
Two international studies involving CIC bioGUNE have advanced new therapeutic strategies for Leigh syndrome using computational biology and artificial intelligence. Published in the journals Nature Communications and Cell, the studies demonstrate how integrating computational models and experimental validation accelerates the understanding of drug mechanisms of action and the discovery of new therapies for rare neurological diseases.
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