USC Researchers Map Genetic Architecture of the Human Corpus Callosum

USC researchers map genetic architecture of the human corpus callosum

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum-the thick band of nerve fibers that connects the brain's left and right hemispheres.

AI tool uncovers genetic blueprint of the brain's largest communication bridge

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum—the thick band of nerve fibers that connects the brain's left and right hemispheres. The findings open new pathways for discoveries about mental illness, neurological disorders and other …

AI Maps the Brain’s Hidden Bridge, Revealing Genetic Links to Mental Health

For the first time, scientists have mapped the genetic architecture of the brain’s communication bridge—the corpus callosum—using AI and MRI data from over 50,000 people. The study uncovered dozens of genes that shape this vital structure’s size and thickness, many active during prenatal development when the brain’s wiring is established.