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AI and nuclear war threaten human extinction by 2100, report warns

The report says two threats could be extinction-level, while climate change, inequality and obesity could each drive billions of healthy years of loss.

  • A Lancet commission of 35 leaders identified 17 interconnected catastrophic threats to global health, warning these dangers could collectively account for tens of billions of years of lost health through the 21st century.
  • Nuclear conflict and the malicious use of artificial intelligence pose extinction-level risks, the commission found. AI impact estimates remain theoretical because "no malicious AI event of a truly global magnitude" has occurred, though industry experts warned such technology could kill humanity.
  • Malicious AI could cause about 10.4 billion healthy years of life lost globally by 2100, while nuclear conflict could wipe out 9.35 billion DALYs. Income inequality could impose a burden equivalent to 25 COVID-19 pandemics, researchers fear.
  • Global threats risk amplifying existing inequalities, with the greatest burden falling on vulnerable communities, Commission Co-Chair Dr. Natalia Kanem said. She noted that recent global shocks show how quickly stability can give way to crisis.
  • Humanity still has the agency to act, said Dr. Christopher Murray, co-chair of the new commission. Murray warned that delaying action will only serve to shift and increase costs into the future, urging immediate world leader intervention.
Insights by Ground AI

194 Articles

Right

What are the biggest threats to humanity? This question has been investigated by an expert commission of the journal "Lancet". It listed 17 threats. At the top: nuclear war and a malicious AI. Less spectacular, but more serious are other, more everyday, dangers.

·Vienna, Austria
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Lean Right

AI and nuclear war could theoretically wipe out humanity. However, a Lancet Commission sees threats that are far more serious than ever before. What is decisive in the list of dangers: how bad it really gets is in the hands of humanity itself.

Scientists have identified the major threats to human health, two of which may lead to extinction

·Kyiv, Ukraine
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Lean Left

An international commission warns governments of 17 dangers with catastrophic potential. Two could, in the extreme, even wipe out humanity.

·Berlin, Germany
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Lean Right

Experts have identified the greatest risks to humanity by the end of the century. They chose the lost years as the basis of their calculations. Two of the scenarios are apocalyptic.

·Berlin, Germany
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IFLScience broke the news in Sudbury, United Kingdom on Saturday, October 10, 2026.
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