Why some Breast Cancers Spread Faster: Jagged1 May Trigger a Tissue-Stiffening Feedback Loop

Why some breast cancers spread faster: Jagged1 may trigger a tissue-stiffening feedback loop

A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer progression. This discovery could offer new treatment opportunities against aggressive forms of breast cancer that currently lack targeted therapy options. The findings are published in the journal Science Advances.

NCCN Guidelines Add Novel Therapeutics to First-Line TNBC Armamentarium

Sacituzumab govitecan and pembrolizumab were recommended as category 1 regimens for metastatic triple-negative breast cancers based on 2 phase 3 trials.

Åbo Akademi University Researchers Uncover Novel Mechanism Driving Breast

A groundbreaking study led by Professor Cecilia Sahlgren and her team at Åbo Akademi University in Finland, alongside the InFLAMES Research Flagship, has unveiled a novel mechanism that orchestrates detrimental remodeling of tumor tissue during the progression of breast cancer. This pivotal discovery paves the way for innovative therapeutic avenues targeting aggressive breast cancer variants, […]