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Some Alzheimer's cases may be caused by copies of a single gene, research shows

  • Scientists have discovered a new genetic form of Alzheimer’s disease, emphasizing the need for specific treatments and prevention methods.
  • Carrying two APOE4 gene variants increases the risk of developing Alzheimer's, particularly in those over 65.
  • Research indicates that individuals with two copies of the APOE4 gene exhibit early signs of Alzheimer's disease and develop symptoms earlier than those with different gene variants.
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People who carry two copies of the APOE4 gene are practically guaranteed to get Alzheimer's disease and face symptoms at an earlier age, scientists said today in a study published in the journal Nature Medicine

·Belgrade, Serbia
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95 percent of people over 65 with mutations have an accumulation of beta-amiloid protein. The ApoE4 variant is not just a risk factor, it's a new genetic form.

·Italy
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Researchers at the Hospital de Sant Pau Institute in Barcelona have identified a new genetic form of Alzheimer's disease that affects almost all people with two copies of the APOE4 gene. The research, published Monday in the journal Nature Medicine, changes the understanding of the effects of this gene and opens the door to new approaches in Alzheimer's research, the most common form of dementia affecting millions of people worldwide.

·Spain
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Nature broke the news in United Kingdom on Monday, May 6, 2024.
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