Some Alzheimer's cases may be caused by copies of a single gene, research shows

A sub­set of Alz­hei­mer’s cases may be caused by two cop­ies of a sin­gle gene, new re­search shows

BOSTON — For the first time, researchers have identified a genetic form of late-in-life Alzheimer’s disease — in people who inherit two copies of a worrisome gene.

95 percent of people over 65 with mutations have an accumulation of beta-amiloid protein. The ApoE4 variant is not just a risk factor, it's a new genetic form.

Researchers identify new genetic form of Alzheimer’s that is present in millions of people

A study involving thousands of patients has found that practically all people with two copies of the APOE4 gene develop biomarkers associated with dementia. Two out of every 100 people carry this variant

People with two copies of a risk gene have genetic form of Alzheimer’s, scientists say

By Julie Steenhuysen CHICAGO (Reuters) – People who carry two copies of the APOE4 gene are virtually guaranteed to develop Alzheimer’s and face symptoms at an earlier age, researchers reported on Monday in a study that could redefine such carriers as having a new genetic form of the mind-wasting disease. The reclassification could change Alzheimer’s research, diagnosis and approaches to treatment, according to the researchers, whose study w…

A gene long thought to just raise the risk for Alzheimer's may cause some cases

WASHINGTON — For the first time, researchers have identified a genetic form of late-in-life Alzheimer’s disease — in people who inherit two copies of a worrisome gene.

Spanish researchers propose in an article published in the journal 'Nature Medicine' a new genetic form of Alzheimer. Experts from Sant Pau Research Institute, led by Juan Fortea, director of the Memory Unit of the Neurology Service of the same hospital, have confirmed that more than 95% of people over 65 years who have two copies of the APOE4 gene - homozygous APOE4 - present Alzheimer's disease biological characteristics in the brain or Alzhei…