Some Alzheimer's cases may be caused by copies of a single gene, research shows
- Scientists have discovered a new genetic form of Alzheimer’s disease, emphasizing the need for specific treatments and prevention methods.
- Carrying two APOE4 gene variants increases the risk of developing Alzheimer's, particularly in those over 65.
- Research indicates that individuals with two copies of the APOE4 gene exhibit early signs of Alzheimer's disease and develop symptoms earlier than those with different gene variants.
50 Articles
50 Articles
A subset of Alzheimer’s cases may be caused by two copies of a single gene, new research shows
BOSTON — For the first time, researchers have identified a genetic form of late-in-life Alzheimer’s disease — in people who inherit two copies of a worrisome gene.
People who carry two copies of the APOE4 gene are practically guaranteed to get Alzheimer's disease and face symptoms at an earlier age, scientists said today in a study published in the journal Nature Medicine
95 percent of people over 65 with mutations have an accumulation of beta-amiloid protein. The ApoE4 variant is not just a risk factor, it's a new genetic form.
Researchers identify new genetic form of Alzheimer’s that is present in millions of people
A study involving thousands of patients has found that practically all people with two copies of the APOE4 gene develop biomarkers associated with dementia. Two out of every 100 people carry this variant
Researchers at the Hospital de Sant Pau Institute in Barcelona have identified a new genetic form of Alzheimer's disease that affects almost all people with two copies of the APOE4 gene. The research, published Monday in the journal Nature Medicine, changes the understanding of the effects of this gene and opens the door to new approaches in Alzheimer's research, the most common form of dementia affecting millions of people worldwide.
People with two copies of a risk gene have genetic form of Alzheimer’s, scientists say
By Julie Steenhuysen CHICAGO (Reuters) – People who carry two copies of the APOE4 gene are virtually guaranteed to develop Alzheimer’s and face symptoms at an earlier age, researchers reported on Monday in a study that could redefine such carriers as having a new genetic form of the mind-wasting disease. The reclassification could change Alzheimer’s research, diagnosis and approaches to treatment, according to the researchers, whose study w…
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