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Tylenol use in pregnancy may be linked with uterus, ovary changes in daughters: Study

Researchers found later pregnancy paracetamol exposure was linked to 23% fewer ovarian follicles in baby girls, while doctors said the drug remains safe when needed.

  • A new study published Wednesday in Human Reproduction Open found girls exposed to acetaminophen in the womb had, on average, 40% smaller ovarian volume, 13% smaller uterine volume, and 23% fewer ovarian follicles.
  • Scientists in Denmark enrolled 685 women during the first trimester of pregnancy, evaluating 302 of their baby girls at 3 months old to assess reproductive development.
  • While noting the findings are "impressive," Dr. Hugh Taylor of the Yale School of Medicine cautioned that the study does not establish acetaminophen exposure causes reproductive organ changes.
  • The American College of Obstetricians and Gynecologists maintains acetaminophen remains the safest medication for pain or fever during pregnancy, advising use only in moderation.
  • Last year, acetaminophen became a political issue when President Donald Trump urged pregnant women to "tough it out" regarding pain, despite established medical consensus supporting the drug's safety.
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36 Articles

ReutersReuters
+4 Reposted by 4 other sources
Center

Tylenol use in pregnancy may be linked with uterus, ovary changes in daughters

Female ​reproductive organ development may be impacted by a mother's use of Tylenol during pregnancy, according to researchers who emphasize that their ‌study does not prove the pain medicine is to blame and does not indicate any effect on the girls’ future fertility.

·London, United Kingdom
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Lean Right

Paracetamol take many pregnant women for pain. A study now shows that the drug can affect the reproductive organs of daughters.

·Berlin, Germany
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Center

Maternal use of paracetamol may give girls smaller ovaries and boys smaller testicles, research suggests

·Copenhagen, Denmark
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Welt broke the news in Berlin, Germany on Tuesday, September 8, 2026.
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