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A single shot of HPV vaccine may be enough to fight cervical cancer, study finds

A study of more than 20,000 girls found one HPV vaccine dose provides 97% protection against cervical cancer infections for at least five years, supporting simpler immunization.

  • On Wednesday, researchers from the U.S. National Cancer Institute and Costa Rica's Agency for Biomedical Research reported a single HPV vaccination appears as effective as two doses at preventing the virus causing cervical cancer.
  • Led by the U.S. National Cancer Institute, over 20,000 girls aged 12 to 16 participated in a trial comparing two HPV vaccines, with a delayed second dose and five-year follow-up, against an unvaccinated group.
  • The findings, published in the New England Journal of Medicine, show a single HPV shot provides about 97% protection, confirming strong protection for five years, according to the U.S. National Cancer Institute and Costa Rica's Agency for Biomedical Research.
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Although most HPV infections go away on their own, some persist and cause cancers that appear years later

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A single shot of HPV vaccine may be enough to fight cervical cancer, study finds

A new study suggests a single HPV vaccination appears just as effective as two doses at preventing the viral infection that causes cervical cancer.

·United States
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Left

While Robert F. Kennedy Jr. has positioned himself against the Gardasil vaccine, two major studies show that papillomavirus vaccines drastically reduce the risk of cervical cancer.

·Paris, France
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NBC Dallas-Fort Worth broke the news in Fort Worth, United States on Tuesday, December 2, 2025.
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