Cheap blood test detects pancreatic cancer before it spreads

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How a cheap blood test may soon detect one of the deadliest cancers

One of the deadliest cancers, pancreatic cancer, can be detected with just a drop of blood. Researchers at Oregon Health and Science University (OHSU) have developed a blood test called PAC-MANN that could detect changes in protease activity. This protein allows tumours to grow by weakening connective tissues

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A pancreatic cancer blood test called PAC-MANN could spot the disease early

The test relies on a magnetic nanoparticle linked to fluorescent molecules to detect pancreatic cancer proteins.

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Cheap blood test detects pancreatic cancer before it spreads

The deadly cancer is often not found until it has spread to other parts of the body. The deadly cancer is often not found until it has spread to other parts of the body.

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Pancreatic cancer is a common cancer, the incidence of which is increasing, especially among women. What are the main risk factors?

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Cheap blood test detects pancreatic cancer before it spreads - 3 Quarks Daily

Smriti Mallapaty in Nature: Fischer and his colleagues focused on detecting enzymes called proteases, which break down proteins and are active in tumours, even from the very early stages. They specifically looked at the activity of matrix metalloproteinases involved in chewing up collagen and the extracellular matrix, which helps tumours to invade the body. To detect the presence of these proteases in the blood, the researchers developed nanosen…

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Cancer of the pancreas is one of the most formidable diseases due to its late diagnosis and high mortality rate. Early detection of this pathology is a major medical issue, as symptoms often appear at an advanced stage, making therapeutic options limited. In this context, a team of [...]