A new reagent makes living brains transparent for deeper, non-invasive imaging

A new reagent makes living brains transparent for deeper, non-invasive imaging

Making a living brain transparent and watching its neurons fire without disturbing their function—sounds like science fiction, doesn't it? Yet the solution may already exist within our own bodies. In a paper published in Nature Methods, a research team led by Kyushu University introduces a new reagent called SeeDB-Live.

Seeing the Brain in a Different Light

Studying living brains has long been a challenge. Techniques like MRI and CT scans can yield some information, but the details are often lost. Even studies of ex vivo brain tissue are often not as detailed as researchers would prefer, due to the density of tissues impairing image quality, even with fluorescence. A research team at Kyushu University, led by Takeshi Imai, PhD, a faculty member in the medical sciences department, has been working o…

Scientists can now see deep-brain activity without disrupting it

Scientists make living brain tissue transparent for imaging. Continue reading Scientists can now see deep-brain activity without disrupting it on Tech Explorist.