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Claude Discovers CRISPR-Like Enzyme System
Claude’s search of 200,000 enzyme clusters found a bacteriophage system with CRISPR-like repeats, and Anthropic says its function remains unknown.
On Wednesday, Anthropic CEO Dario Amodei announced that Claude, its AI system, discovered a previously unknown enzyme system in DNA that may constitute a new gene editing mechanism with applications in gene therapy.
Some 950 Claude-powered software agents analyzed DNA sequences for 21 hours, scanning more than 200,000 genes to identify 20 candidates—work that would typically require weeks of laboratory effort.
Beside the enzyme's gene sits a long array of repeating DNA, a structure resembling CRISPR, the natural defense system bacteria use to modify living organisms.
Feng Zhang, a professor at MIT and the Broad Institute, called the findings 'genuinely intriguing' and said the discovery 'merits further investigation,' though results remain preliminary and unpeer-reviewed.
Anthropic dubbed the newly identified system ART, and Amodei stated the finding is 'Preliminary,' suggesting AI could eventually autonomously control lab equipment to accelerate drug discovery research.
The Claude language model has independently discovered a structure that resembles that of CRISPR, although "it still takes much more work to learn what this system does and if it can have a similar use" Read