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194-year-old tortoise reveals stable gene switches that may help resist aging: Study
On Wednesday, October 7, 2026, researchers published the first genome sequence of Jonathan, the 194-year-old Aldabra giant tortoise, in the journal Science Advances, revealing genetic mechanisms driving his extreme longevity.
Hatched in about 1832, Jonathan has spent 144 years on St. Helena in the South Atlantic Ocean after being purchased as a gift, establishing him as the world's oldest known land animal.
Researchers found that chemical tags near 272 of Jonathan's genes remained tidy, mirroring those of much younger tortoises and suggesting resilience against age-related decline through preserved DNA repair and mitochondrial regulators.
Stephen Clark, lead author of the study, stated the team aims to translate evolutionary insights into practical treatments for chronic disease, with research supported by the Stephen Voland Research Fund offering a cellular resilience blueprint.
Scientists caution that the study, which analyzed only five tortoises, remains a hypothesis rather than proven cause of long life, with further testing needed to determine if these genetic patterns truly protect against aging.