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World's first vaccine trial against elephant endotheliotropic herpesvirus proves safe and effective

The vaccine trial in adult elephants showed no side effects and induced a strong immune response, a key step toward protecting vulnerable calves from EEHV, which kills over 80% of infected juveniles.

Summary by News Medical
The world's first vaccine trial against elephant endotheliotropic herpesvirus (EEHV) – a leading cause of death in young Asian elephants – is safe and triggers a strong virus-fighting immune response, according to an international team led by the University of Surrey, in collaboration with Chester Zoo and the Animal and Plant Health Agency.
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The first global test of an elephant herpes endotheliotropic virus (EHEV) vaccine, one of the leading causes of death among the offspring of this species, has triggered a strong immune response and seems to be effective. The entry Successfully test a herpes lethal vaccine for elephants was first published in the Digital Process.

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BBC News broke the news in United Kingdom on Friday, October 3, 2025.
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