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Surgeons in California Perform First-Ever Human Bladder Transplant

  • On May 4, 2025, surgeons from UCLA and USC successfully completed the first-ever human bladder transplant at Ronald Reagan UCLA Medical Center.
  • The surgery responded to limitations of current treatments that use intestinal tissue for urinary function, which often causes complications in 80% of cases.
  • The eight-hour procedure transplanted both a donor bladder and kidney into 41-year-old Oscar Larrainzar, who had lost his bladder and kidneys to cancer and kidney failure.
  • Doctors reported immediate kidney function improvement and natural urination within days, with Dr. Gill calling it a "successful" surgery done "according to plan."
  • This pioneering transplant offers hope for patients with severe bladder damage, though it requires immunosuppression and carries risks, so surgeons will continue a small clinical trial before wider use.
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Scienmag: Latest Science and Health News broke the news in on Sunday, May 18, 2025.
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