US EditionWhy vaccines work less well as we age
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Older adults often respond less strongly to vaccines, from the annual flu shot to COVID boosters. We now know why. In the lab, researchers at the Allen Institute discovered that certain T cells shift to a different "mode" of the cell's gene program as we age. This changes how those T cells provide support to B cells, the cells […] Want to learn more about science? Read the latest articles on Scientias.nl .
Why vaccines work less well as we age
As flu season returns and vaccines are rolled out, researchers at the Allen Institute are uncovering why vaccines don’t work as well in older adults—and what can be done to improve them. Their findings may help create better vaccines for everyone, especially those over the age of 65. In the largest study of its kind, […] The post Why vaccines work less well as we age appeared first on Knowridge Science Report.
As we age, our immune system does not respond to vaccines in the same way. A new study published in Nature has identified the cellular mechanisms that explain why those over 65 years of age develop a weaker response after vaccination and offers clues to improve their effectiveness. In the broader research of this type, scientists analyzed how T cells — those responsible for coordinating the immune response — change throughout aging. The work sho…
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