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US Overdose Deaths Decline in 45 States Through August 2025

Federal data shows a 21% drop in overdose deaths to about 73,000 in 12 months ending August 2025, marking the largest decline recorded in over two years.

  • U.S. overdose deaths fell through most of 2025, suggesting a lasting improvement in an epidemic that had been worsening for decades.
  • Overdose deaths peaked nearly 110,000 in 2022, fell a little in 2023 and then plummeted 27% in 2024, to around 80,000.
  • University of Maryland researchers point to regulatory changes in China a few years ago appear to have diminished the availability of precursor chemicals used to make fentanyl.
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US overdose deaths fell through most of 2025, federal data reveals

U.S. overdose deaths fell through the most of last year, suggesting a lasting improvement in an epidemic that had been worsening for decades.

·United States
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Winnipeg Free Press broke the news in Winnipeg, Canada on Wednesday, January 14, 2026.
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