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Tiny silica particles wiped out aggressive prostate cancer in mice
In mice, the silica particles also reprogrammed tumor immunity and boosted checkpoint therapy, producing complete or near-complete remissions in 5 of 10 animals.
Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the immune system in preclinical mouse studies. Combined with immunotherapy, the treatment produced complete remissions in multiple mice, raising hopes for a powerful new approach to prostate cancer.