Blood Protein Signature Can Predict Lung Cancer Risk Before Diagnosis
Researchers said the test outperformed current risk models and nearly halved lung cancer risk in a high-expression drug trial subgroup.
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Scientists have made a discovery that could help prevent some people from developing lung cancer, which is the type of cancer that kills more people around the world. A team of more than 80 researchers working on four continents has identified a set of proteins in the blood that accurately predict lung cancer more than five years before diagnosis. Scientists also found preliminary indications that an existing anti-inflammatory drug could signifi…
Blood test spots 14 proteins that predict lung cancer risk up to five years early
As we age, our cells acquire cancer-causing mutations, but mutations alone are rarely enough to start a tumor. An environmental trigger, such as exposure to air pollution from sources such as combustion engines, coal burning and cigarette smoke may be needed to tip mutant cells into cancer. Currently, lung cancer screening is offered only to people over a certain age who have previously smoked, missing never-smokers and individuals exposed to high levels of pollutants who may also be at risk of the disease.
Blood protein signature can predict lung cancer risk before diagnosis
Researchers at the Francis Crick Institute and University College London (UCL), funded by Cancer Research UK and the European Research Council (ERC), have identified a 14-protein signature in the blood that can predict lung cancer risk more than five years before diagnosis.
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