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One Study Shows that It Is Safe to Space Colonoscopy Three to Five Years After Removal of Polyps

The European polyp surveillance trial (EPoS), led by Miguel Hernández de Elche University (UMH), has shown that colonoscopy surveillance following the removal of high-risk polyps can be delayed safely from 3 to 5 years. The results, published in two scientific papers in The New England Journal of Medicine, suggest a direct optimization in the screening process of colorectal cancer that will positively affect millions of people.
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The EPoS II clinical trial, conducted in nearly 11,000 patients in eight countries, suggests that a five-year surveillance colonoscopy would provide safety comparable to a three-year control.

A colonoscopy every three years after removing a high-risk polyp may not be necessary in all cases. A European study led from Alicante by researchers from the Isabial Institute and the Miguel Hernández University proposes to space up to five years the first surveillance colonoscopy, without this having led to an increase in the diagnosis of colorectal cancer during the first five years of follow-up.

The European polyp surveillance trial (EPoS), led by Miguel Hernández de Elche University (UMH), has shown that colonoscopy surveillance following the removal of high-risk polyps can be delayed safely from 3 to 5 years. The results, published in two scientific papers in The New England Journal of Medicine, suggest a direct optimization in the screening process of colorectal cancer that will positively affect millions of people.

Delaying from three to five years the first surveillance colonoscopy after the removal of high-risk polyps, such as advanced adenomas, does not increase the risk of developing colorectal cancer or dying from this disease, according to a study recently published in The New England Journal of Medicine. The trial has included a total of [...] The entry Delaying 3 to 5 years a surveillance colonoscopy could be safe for patients with high-risk polyps…

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EfeSalud broke the news on Tuesday, September 22, 2026.
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