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Suidae iPSC-derived macrophages as models for investigating susceptibility and resilience to African swine fever virus
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Suidae iPSC-derived macrophages as models for investigating susceptibility and resilience to African swine fever virus
Suidae iPSC-derived macrophages as models for investigating susceptibility and resilience to African swine fever virus African swine fever virus (ASFV) causes a lethal hemorrhagic fever in pigs, and spread of this disease threatens many pig species (Suidae) globally. By contrast, ASFV infections in the natural evolved hosts, warthog and bushpig, are subclinical. The macrophage (Mϕ) is the primary target of ASFV, and species-dependent responses i…
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