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Report Finds Substantial Progress Made Against Childhood Cancers

Survival rates for childhood cancers in the U.S. have risen to 87%, but lethal tumors and health disparities persist, the AACR report states.

  • On Dec. 4, 2025, the American Association for Cancer Research released its first Pediatric Cancer Progress Report, finding five-year survival rose to 87% in 2015–2021 from about 63% in the mid-1970s.
  • Advances such as CAR T-cell therapy and pediatric-specific drug approvals increased up to 2025, with many targeted therapies approved by the U.S. Food and Drug Administration, AACR reports.
  • Leanna's case shows that after chemotherapy left her marrow with over 70% leukemia cells and a chemo-resistant mutation, she received CAR T therapy, leading to near remission.
  • The report warns nearly 15,000 U.S. children and teens will be diagnosed in 2025, with survivors facing chronic health burdens and disparities by race and geography, including `over 70%` developing at least one condition.
  • AACR is calling for expanded data sharing, international clinical trials, and sustained NIH and NCI funding, Dr. Margaret Foti said, to address remaining pediatric cancer gaps.
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Substantial Progress Made Against Childhood Cancers, Report Says

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KULR-TV broke the news in Billings, United States on Friday, December 5, 2025.
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