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Early IBD Linked To Changes In Gut Bacteria, Evidence Shows
Researchers analyzed data from over 1,700 patients and found that mouth bacteria migrating to the gut may trigger inflammation and early microbial changes in inflammatory bowel disease.
- On Dec. 30, 2025, an evidence review found early shifts in gut bacteria may mark the start of inflammatory bowel disease, HealthDay reported from University of Birmingham.
- Researchers found that patients with Crohn's disease and ulcerative colitis lose beneficial anaerobes while oxygen-tolerant mouth bacteria, including Granulicatella and Haemophilus, increase, supporting the oxygen hypothesis.
- Synthesizing 36 previous studies, the review combined data from more than 1,700 recently diagnosed children and adults across 11 countries and appears in Gastroenterology.
- These findings suggest treatment paths such as therapies lowering gut oxygen or restoring healthier gut bacteria, and researchers said this could help doctors diagnose IBD earlier.
- Published as the first clear cross‑dataset demonstration, the study shows gut oxygen changes and mouth‑to‑gut bacterial migration may trigger inflammation and inform future screening and therapies for IBD.
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Early IBD Linked To Changes In Gut Bacteria, Evidence Shows
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Coverage Details
Total News Sources26
Leaning Left3Leaning Right4Center8Last UpdatedBias Distribution53% Center
Bias Distribution
- 53% of the sources are Center
53% Center
L 20%
C 53%
R 27%
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