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Single Gene Knockout Strips Lab-Grown Heart Cells of Immune Visibility

Summary by BIOENGINEER.ORG
Researchers used CRISPR-Cas9 to knock out the TAPBP gene in human induced pluripotent stem cells, producing cardiomyocytes with sharply reduced HLA class I expression that evaded cytotoxic T cells without triggering natural killer cell attack.
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BIOENGINEER.ORG broke the news on Sunday, October 18, 2026.
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