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Secret of Orange Cats Finally Revealed After 60-Year Search

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Scientists have uncovered the genetic mechanism that explains the orange fur color in cats. Two independent research teams from Stanford University and Kyushu University determined that the color is associated with a DNA deletion of approximately 5 kilobases in the regulatory region of the Arhgap36 gene. 🚆

Scientists have finally solved the genetic mystery that causes orange fur in cats after 60 years. Research from Stanford and Kyushu Universities determined that the orange coat color is caused by a 5-kilobyte DNA deficiency in the Arhgap36 gene, which converts the color pigments into yellow-red tones.

Red cats have remained a mystery to geneticists for decades. Now, scientists have discovered a feature of DNA that not only explains their coloration, but also helps to understand why completely red cats are significantly smaller than males.

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Science Alert broke the news in Canberra, Australia on Friday, October 9, 2026.
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