Study Reveals Bacterial Strategy Behind Antibiotic Tolerance and Persistence
Using a compound first found in 2020, researchers restored vancomycin’s activity against drug-resistant E. faecium and pointed to a broader adjuvant strategy.
8 Articles
8 Articles
Scientists revive a powerful antibiotic that superbugs had defeated
Scientists have found a way to revive vancomycin, a powerful antibiotic that some dangerous bacteria have learned to resist. Instead of creating an entirely new drug, researchers paired vancomycin with a small molecule called pghi-4, which blocks a bacterial enzyme linked to resistance. The combination restored the antibiotic’s ability to kill drug-resistant E. faecium, raising hopes that similar chemical helpers could rescue other failing medic…
New study identifies strategy to tackle antimicrobial resistance
A new study has identified a promising strategy to tackle antimicrobial resistance by making multidrug-resistant bacteria more vulnerable to existing antibiotics, potentially allowing doctors to treat life-threatening infections with lower and safer drug doses. The research, led by Professor Kwang-sun Kim of the Department of Chemistry and the Chemistry Institute for Functional Materials at Pusan […] The post New study identifies strategy to tac…
Changes in RNA Regulation Enable Bacteria to Enter Antibiotic Tolerance
Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics. St. Jude Children's Research Hospital scientists have uncovered how S. pneumoniae adapts to antibiotic exposure and immune pressures.
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