DNA Damage in Gray Matter Neurons Linked to MS Progression

DNA damage in gray matter neurons linked to MS progression

For decades, multiple sclerosis research has focused on myelin, the insulation around the brain's wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying.

New Breakthrough In Multiple Sclerosis Science Reveals Some Brain Cells Are Killed By Uncontrollable DNA Damage

Multiple sclerosis largely affects the brain’s internal “wiring”, but two new studies have found it also kills neurons by a previously unknown mechanism.

Scientists discover how multiple sclerosis kills neurons

For decades, multiple sclerosis research has focused on myelin, the insulation around the brain's wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying.