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Scientists build synthetic cell from scratch that can feed, grow and replicate

  • University of Minnesota Twin Cities synthetic biologist Kate Adamala and her team constructed SpudCell, a synthetic droplet capable of feeding, growing, and replicating like a natural cell.
  • Made of 150 to 200 molecules and 36 genes, SpudCell relies on a 90,000 base pair genome to replicate every 12 hours at 30 degrees Celsius, far slower than natural bacteria.
  • Researchers encoded division using FLAG surface tags, yet ribosomes degrade over time and only 30% of SpudCells retained the full genome after five division cycles.
  • Following the research, synthetic biologist Drew Endy and Adamala founded Biotic, a public-benefit institution that secured $10 million in seed money to accelerate synthetic cell development.
  • Although SpudCell remains a limited prototype unable to evolve, scientists suggest synthetic cells could eventually enable new cancer treatments, carbon capture, or chemical manufacturing.
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They are capable of recreating the entire life cycle of an organism. Scientists led by Dr. Kate Adamala from the University of Minnesota have announced the biggest breakthrough in synthetic biology in recent memory. They have assembled artificial cells, dubbed SpudCells, from scratch. This was reported by RBC-Ukraine, citing The Guardian. The anatomy and evolution of SpudCells: how chemistry becomes biology To fully control and understand every …

Researchers at the University of Minnesota developed SpudCell, a synthetic cell that grows, reproduces and divides its genetic material. The goal is living artificial life with applications in medicine and the environment.

·Munich, Germany
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Science broke the news on Wednesday, July 1, 2026.
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