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Revolution Medicines says its potential breakthrough pancreatic cancer drug succeeds in late-stage trial

The daily pill cut the risk of death by 60% and raised median survival to 13.2 months, RevMed said.

  • Revolution Medicines announced Monday that its experimental pill reduced the risk of death by 60% in a Phase 3 Pancreatic cancer trial, with RevMed CEO Mark Goldsmith calling the results "dramatic, practice-changing outcomes."
  • RAS mutations found in more than 90% of Pancreatic cancer cases drive tumor growth, which the pill targets as an alternative to cytotoxic intravenous chemotherapy, the standard treatment.
  • Patients taking the pill lived 13.2 months versus 6.7 months on chemotherapy, an increase of 6.5 months, with Goldsmith noting no drug has previously shown such an overall survival benefit in a Phase 3 pancreatic trial.
  • The company plans to seek Food and Drug Administration approval using a National Priority Voucher that expedites review, and Shares jumped more than 30% following Monday's announcement.
  • Despite media reports identifying the company as a potential acquisition target, Revolution Medicines is conducting a Phase 3 trial for newly diagnosed patients to expand the pill's reach.
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Pancreatic cancer pill shown to nearly double overall survival time, drug company says

The company reports the drug showed “clinically meaningful improvements” in overall survival.

·Cleveland, United States
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The Hamilton Spectator broke the news in Hamilton, Canada on Monday, April 13, 2026.
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