In a lab at the University of Yamanashi, one mouse line kept coming back in a form that looked almost unchanged. Researchers began with a single female donor and used her cells to make a clone, then repeated the same process with the clone’s cells, again and again, over 20 years. The animals kept the same sex and the same agouti coat color, which gave the project an eerie sense of continuity as the generations stacked up. The work moved forward …
There is a biological limit on the cloning of mammals, the Japanese researchers highlighted in a published study in March, which mentions a risk of “mutational collapsing”, as such “dubination in series” causes serious genetic mutations...