49ers Offense Has Little Margin for Error with so Many Injuries to the Defense

Injury-riddled 49ers defense crumbles as Rams score 6 touchdowns in blowout win

The way Matthew Stafford and the Los Angeles Rams picked apart the injury-riddled defense for San Francisco, it raised questions about why the 49ers weren’t more aggressive before last week’s trade deadline.

The 7 Biggest Takeaways From the 49ers' 42-26 Loss to the Rams

Coming back to win after being down 21-0 early was too much for the 49ers to overcome against the Rams. Here are the seven takeaways that stood out the most in their loss.

Rams 42, 49ers 26: Injury-thinned defense yields most points this season

SANTA CLARA – The 49ers flirted Sunday with what would have been the largest comeback in coach Kyle Shanahan’s nine seasons. Alas, the offense didn’t score nearly enough to offset the six touchdowns allowed by their thinned-out defense. The Los Angeles Rams, after jumping out to a 21-0 lead, scored more than any 49ers opponent this season in claiming a 42-26 victory at Levi’s Stadium. Instead of sweeping the season series against the Rams (7-2),…

Kyle Shanahan sends strong message to 49ers after costly loss to Rams

The San Francisco 49ers suffered a potentially pivotal defeat on Sunday, falling 42-26 to the Los Angeles Rams in a game that could have reshaped the NFC West standings. Instead, the loss left San Francisco searching for answers as it looks to keep pace with the division-leading Rams and Seattle Seahawks. After defeating the Rams earlier this season in Week 5, the 49ers looked to repeat that success at Levi's Stadium. However, head coach Kyle S…

What we learned as the 49ers' depleted defense gets diced up in costly divisional loss to Rams

The Los Angeles Rams scored touchdowns on their first three drives, and the San Francisco 49ers never were able to dig themselves out of that hole.

Rams vs. 49ers: Live Updates, Score From 'America's Game of the Week'

One of the NFL's most competitive divisions takes center stage on “America's Game of the Week" this Sunday.