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Psilocybin might not be the most psychoactive ingredient in magic mushrooms, new research suggests

Summary by PsyPost
Published in Scientific Reports, new research provides evidence that minor compounds in psychedelic mushrooms work alongside psilocybin to interact with brain receptors. This chemical teamwork explains why whole mushroom extracts often affect people differently than isolated, lab-made psilocybin.

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Psilocybin might not be the most psychoactive ingredient in magic mushrooms, new research suggests

Published in Scientific Reports, new research provides evidence that minor compounds in psychedelic mushrooms work alongside psilocybin to interact with brain receptors. This chemical teamwork explains why whole mushroom extracts often affect people differently than isolated, lab-made psilocybin.

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PsyPost broke the news in on Monday, March 16, 2026.
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