Preclinical models map genetic changes behind multiple sclerosis nerve damage

Preclinical models map genetic changes behind multiple sclerosis nerve damage

More than 1 million people across the United States live with multiple sclerosis (MS), a disease that affects the brain, optic nerves and spine.

Genetic Maps Target Root Causes of Multiple Sclerosis

A new study provides the first direct empirical comparison of the two primary preclinical models for myelin loss and regeneration: cuprizone (CPZ) and lysophosphatidylcholine (LPC).

Multiple Sclerosis Myelin Loss Revealed by Transcriptomic Analysis in Mice

More than one million people across the United States live with multiple sclerosis (MS), a disease that affects the brain, optic nerves, and spine. MS is characterized by overwhelming fatigue, muscle spasms, and vision problems, which can flare up and then subside over days, months, or even years. Studying the underlying damage to the nervous system is key to identifying new treatment paradigms for MS.  A new study published in Nature Communicat…