US EditionPopular sugar substitute could raise the risk of blood clots and stroke
U.S. AND EUROPE, JUL 14 – A study of 4,000 people in the U.S. and Europe found higher erythritol levels linked to increased risk of heart attack and stroke within three years, researchers said.
- New research from the University of Colorado Boulder shows that erythritol damages brain blood vessel cells, potentially raising stroke and blood clot risk.
- In lab experiments, researchers exposed human cerebral microvascular endothelial cells to a 30 g erythritol dose, reducing nitric oxide, increasing constrictors, and impairing clot-busting pathways.
- Assays indicated reactive oxygen species rose 204% within three hours in treated cells, and t-PA release was blunted when exposed to thrombin.
- In a human epidemiological study of 4,000 people, higher erythritol levels were linked to increased risk of heart attack or stroke within three years, and these cellular changes create a higher risk environment for clotting and reduced cerebral blood flow.
- Looking ahead, researchers caution that larger human trials are needed, and consumers should check labels for erythritol or `sugar alcohol`.
12 Articles
12 Articles
This Popular Zero-Calorie Sweetener Could Impair Brain Blood Vessel Cells, Study Suggests
That zero-calorie sweetener making your morning coffee taste just right might be quietly interfering with the tiny blood vessels in your brain. The post This Popular Zero-Calorie Sweetener Could Impair Brain Blood Vessel Cells, Study Suggests appeared first on Study Finds.
Study: Common Sweetener Erythritol May Impact Brain Cells and Elevate Stroke Risk
A recent study from the University of Colorado Boulder indicates that erythritol, a widely used non-nutritive sweetener, may be linked to a higher risk of cardiovascular and cerebrovascular events. Berry et al. Our study demonstrates that erythritol, at concentrations commonly found in standard size sugar-free beverages, negatively impacts cerebral microvascular endothelial cell oxidative stress, ENOS [...] The post Study: Common Sweetener Eryth…
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