PASTE Expands CRISPR Toolbox by Inserting Large Pieces of DNA
Summary by Ground News
PASTE (programmable addition via site-specific targeting elements) delivered genes as long as 36,000 DNA base pairs to several types of human cells. PASTE uses a CRISPR-Cas9 nickase fused to two enzymes. Researchers are now exploring the possibility of this tool as a possible way to replace the defective fibrosis gene.Published 2 months ago
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