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No clear link between acetaminophen use during pregnancy, autism: Review

A UK-led umbrella review rated most prior studies as low confidence and found that familial genetics explain apparent links between prenatal acetaminophen and autism or ADHD.

  • A systematic review shows no clear link between acetaminophen use during pregnancy and neurodevelopmental disorders, stating it does not increase autism or ADHD risk in children.
  • Researchers reported low confidence in earlier studies about the association between acetaminophen and neurodevelopmental disorders, with reliability ratings described as low to critically low for the studies reviewed.
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Medical Xpress broke the news in on Thursday, November 6, 2025.
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