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NICE Approves Teplizumab for Early-Stage Type 1 Diabetes on NHS

The one-time immunotherapy can delay symptomatic type 1 diabetes by nearly three years, NICE said, giving patients more time before insulin treatment is needed.

  • The National Institute for Health and Care Excellence approved Teplizumab for NHS use in England and Wales, marking a "landmark" moment for early-stage type 1 diabetes treatment.
  • Known as Tzield, the immunotherapy trains the immune system to stop attacking pancreatic cells, delaying symptomatic type 1 diabetes by an average of nearly three years.
  • Administered via a 14-day daily infusion, the treatment is approved for patients aged eight and over who are in the early stages before symptoms appear.
  • NICE estimates around 1,100 people could be eligible in the first year, with approximately 820 patients annually thereafter, offering families precious extra time without insulin management.
  • While The Early Surveillance for Autoimmune Diabetes and T1DRA studies screen eligible patients, NICE guidance does not apply in Northern Ireland; the Scottish Medicines Consortium expects advice by early 2027.
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Diabetes breakthrough as NHS treatment stops disease for three years

The therapy has been approved for use by the National Institute for Health and Care Excellence

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The Sun broke the news in United Kingdom on Monday, June 22, 2026.
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