US EditionNerve Pain Medication Gabapentin Possibly Tied to Dementia, Study Says
UNITED STATES, JUL 11 – A large US study found adults aged 35-64 prescribed gabapentin had over twice the risk of dementia, with risk increasing alongside prescription frequency, researchers said.
- On July 10, the journal Regional Anesthesia & Pain Medicine published a large observational study, drawing on TriNetX network data, linking frequent gabapentin prescriptions to increased dementia and MCI risks.
- The drug suppresses communication between nerve cells, raising cognitive decline concerns, researchers said in background notes.
- Patients prescribed gabapentin six or more times face a 29% higher dementia and 85% higher MCI risk, especially in adults aged 35–49, according to US scientists.
- Healthcare providers are being advised to monitor cognition and consider physiotherapy or nerve blocks for middle-aged gabapentin users.
- As an observational analysis, the study's design means no firm conclusions about causality can be drawn, and previous research has shown mixed results, highlighting ongoing debate.
25 Articles
25 Articles
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