US EditionNerve Pain Medication Gabapentin Possibly Tied to Dementia, Study Says
USA, JUL 11 – Patients receiving six or more gabapentin prescriptions have a 29% higher dementia risk and 85% higher risk of mild cognitive impairment, researchers found in a large US study.
- A recent study in Regional Anesthesia & Pain Medicine, published July 10, analyzing US electronic health records, associates gabapentin with increased dementia and MCI risks.
- Building on large-scale US data, six or more gabapentin prescriptions are linked to 29% higher dementia and 85% higher MCI risks in 26,414 patients versus non-users.
- Studies show nonelderly gabapentin users have over twice the risk of dementia and MCI , with risks rising with prescription frequency.
- In light of these findings, experts recommend close monitoring of adult patients on gabapentin for cognitive decline and potential brain health side effects.
- Despite limitations of observational, retrospective data and mixed findings, the study underscores the urgent need for further research into gabapentin's long-term cognitive effects.
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18 Articles
Impact of prescribed opioid use on development of dementia among patients with chronic non-cancer pain
We aimed to examine the association between opioid use and the development of dementia in patients with chronic non-cancer pain in South Korea. Data were extracted from the National Health Insurance Service database in South Korea. Adult patients diagnosed with musculoskeletal diseases with chronic non-cancer pain between 2010 and 2015 were included in the analysis. Patients who were prescribed opioids regularly and continuously for ≥ 90 days we…
News Medical
Industrial NewsFrequent gabapentin use linked to higher dementia and cognitive impairment risk
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)--29% and 85%, respectively-finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.
Medical Xpress
Medical DialoguesNerve pain drug gabapentin linked to increased dementia, cognitive impairment risks
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.
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