Tecovirimat monotherapy found ineffective for treating clade II mpox in NIH-sponsored trial
- A case of mpox was identified in a patient who visited Addenbrooke's Hospital emergency department on April 12, 2025, in Cambridge, UK.
- The patient had no recent travel history or connections to other cases, leading the hospital to identify and notify a group of patients and healthcare workers as a precautionary measure.
- Mpox, caused by a virus related to smallpox, spreads primarily through intimate, person-to-person contact and usually causes mild illness resolving within weeks without treatment.
- A representative stated that following the visit of an individual with Mpox to their emergency unit on the evening of Saturday, 12 April, they have reached out to approximately 30 patients and 20 staff members as a safety precaution.
- The hospital and UK Health Security Agency are monitoring the situation; the patient is isolating at home and under GP care, while the risk to the general UK population remains low.
29 Articles
29 Articles
A front-line antiviral drug disappoints against worrisome monkeypox strain
Tecovirimat, which has been approved to treat mpox, was no better than a placebo in a large trial. Tecovirimat, which has been approved to treat mpox, was no better than a placebo in a large trial.

Congo faces setback in mpox response after Rwanda-backed rebels advance in the east
Hospitals across eastern Congo that were once at the forefront of the country’s response to the mpox outbreak are facing a setback in detecting the disease and offering treatment following the advance of Rwanda-backed rebels in the region.
Congo-Kinshasa: DR Congo Fighting Forces Hundreds of Mpox Patients to Leave Treatment Centres
Monrovia -- More than 600 people infected with mpox left treatment centers in the Democratic Republic of Congo due to fighting in the eastern part of the country, the African Centers for Disease Control said during an online briefing on the status of the disease on March 6. The continental health body said, although more than 150 of those who ran away returned in the eastern city of Bukavu - following a relative improvement in security - they st…
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