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Microsoft's AI diagnostic system correctly solved up to 85.5% of 304 exceptionally difficult medical cases adapted from the New England Journal of Medicine — while 21 experienced physicians averaged just 20% under the same benchmark conditions.
Microsoft reported an eye-catching result in June 2025: its experimental diagnostic orchestrator, paired with OpenAI’s o3 model, correctly solved as many as 85.5% of 304 exceptionally difficult medical cases adapted from the New England Journal of Medicine. The 21 experienced physicians recruited for the comparison averaged 19.9% across the cases they completed. This is research reporting, not medical advice, and the system is not a substitute f…
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