Measuring blood levels of toxic TDP-43 protein in astrocyte-derived extracellular vesicles — packets of cellular material released from star-shaped brain support cells called astrocytes — may help diagnose amyotrophic lateral sclerosis (ALS), according to a new study from U.S. researchers. Tests showed that differences in TDP-43 levels inside these extracellular vesicles accurately distinguished ALS patients from healthy individuals, the scienti…
International researchers study whether degeneration starts in motor neurons, muscle, or other components of the body to advance towards an early diagnosis