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Psilocybin For Depression Effective Up To Five Years After Treatment
Two-thirds of patients remained free of major depressive disorder symptoms five years after psilocybin-assisted therapy combined with psychotherapy, suggesting lasting treatment efficacy.
- A five-year follow-up found most patients with major depressive disorder remained symptom-free, with two-thirds in complete remission, American scientists report.
- In 2021, the original clinical trial found 24 participants received two doses of psilocybin combined with psychotherapy for major depressive disorder, and 18 enrolled in long-term follow-up.
- Data showed 67% were in remission at five years compared to 58% at one year, with Professor Alan Davis noting, `Most people continued to view this treatment as safe, meaningful, important, and something that catalyzed an ongoing betterment of their life.`
- Follow-Up assessments found 11 participants reporting no adverse effects, but authors warned remission cannot be attributed solely to the 2021 trial due to use of antidepressants, other psychedelics, ketamine, or psychotherapy afterward.
- Study authors cautioned that the small sample limits firm conclusions and highlighted the therapist–participant relationship as a potential key factor in lasting improvement, as reported by participants.
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InsideNoVA.com+24 Reposted by 24 other sources
Psilocybin For Depression Effective Up To Five Years After Treatment
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Coverage Details
Total News Sources27
Leaning Left8Leaning Right3Center5Last UpdatedBias Distribution50% Left
Bias Distribution
- 50% of the sources lean Left
50% Left
L 50%
C 31%
R 19%
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