Inherited EGFR Mutation Raises Lung Cancer Risk in Nonsmokers
4 Articles
4 Articles
The researchers studied a rare mutation T790M in the EGFR gene. It turned out that people with this mutation had about a 25-fold higher risk of developing lung cancer compared to those who did not have the mutation — regardless of whether they smoked or not.
Researchers have highlighted the role of hereditary genetic mutation in the occurrence of lung cancer - particularly among non-smokers - which could help to better understand the development of this disease – and above all, to better diagnose it.
A mutation in the EGFR gene would significantly increase the risk of lung cancer. On September 17, 2026, scientists from the Dana-Farber Cancer Institute in the United States measured its impact on more than 3 million DNA profiles. Hereditary, the variant is concentrated in the southeastern United States. No known hereditary factor weighs as much on the risk of lung cancer. Screening criteria, so far based on smoking alone, may evolve. EGFR T790…
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