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Lithium uncovers fresh Alzheimer's targets beyond Tau
The study found lithium chloride changed multiple Alzheimer’s-related phosphosites and predicted shifts in several kinases and Rho GTPases.
Summary by Medical Xpress
3 Articles
3 Articles
Unlocking lithium's hidden effects on Alzheimer's disease at the cellular level
Lithium salts have shown promise in treating Alzheimer’s disease by preventing certain proteins in the brain from clumping together, but how they affect cells on a broader scale remains largely unexplored. A recent study published in the journal Biomedicine & Pharmacotherapy reveals that lithium chloride alters multiple cellular pathways beyond its primary target, changing the activity of various enzymes and structural proteins linked to dementi…
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