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Eggs fertilized with material from human skin cells for first time

OHSU researchers created 82 fertilizable eggs from skin cells, with 9% reaching early embryo stage, marking a key step toward infertility treatments for women and same-sex couples.

  • Scientists at Oregon Health and Science University have developed a technique that converts DNA from skin cells into human eggs, allowing older women to potentially have children in the future.
  • The experimental research shows promise but warns that while the technique still shows chromosome abnormalities, further studies are needed to address these issues before clinical trials can begin.
  • Approximately 9 percent of the created cells reached the blastocyst stage, indicating that more research is necessary to ensure safety.
  • Dr. Paulo Amato highlighted that this technology could help same-sex couples have children genetically related to both partners, but cautioned against older women carrying pregnancies due to health risks.
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American scientists have created early human embryos for the first time by manipulating DNA taken from human skin cells and then fertilizing them with sperm. The technique could overcome infertility due to age or disease. The method could theoretically allow same-sex couples to have genetically related children. But researchers still have many years of work ahead of them.

Lean Left

Researchers have changed human skin cells in such a way that they could be fertilized with sperm. Older women or same-sex couples could open up completely new possibilities.

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Lean Left

The method can help with infertility and allow same-sex couples to have a child genetically related to them, but it still takes time for it to work well.

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ohsu.edu broke the news in on Tuesday, September 30, 2025.
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