Lab demonstrates key molecular factor in exhaustion of immune cells—with treatment implications

Lab demonstrates key molecular factor in exhaustion of immune cells—with treatment implications

A key enzyme and its molecular pathway are critical to keeping certain immune cells active and away from "exhaustion," according to a new study published in the Proceedings of the National Academy of Science.

CDI Lab Identifies Key Molecular Driver of Immune Cell Exhaustion, Opening

In a groundbreaking study recently published in the prestigious Proceedings of the National Academy of Sciences, immunologists have unveiled a critical molecular mechanism by which activated CD8+ T cells maintain their functionality and resist the onset of exhaustion during chronic viral infections. Led by Hai-Hui “Howard” Xue, Ph.D., at the Hackensack Meridian Center for Discovery and Innovation (CDI), the research sheds new light on the role o…