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Junshi Biosciences Announces Completion of First Patient Dosing in the Phase 3 Clinical Trial ...

The study will enroll 282 patients and uses overall survival as the primary endpoint after encouraging early results and manageable safety in Phase 1.

  • On Friday, Shanghai Junshi Biosciences completed first patient dosing in a Phase 3 clinical trial of JS203, a bispecific antibody designed to treat relapsed or refractory DLBCL.
  • DLBCL accounts for approximately 40% of adult NHL cases in China, with approximately 45,000 new cases annually characterized by high aggressiveness and rapid progression.
  • JS203 demonstrated a 69.7% objective response rate in DLBCL patients during Phase 1 trials, with a manageable safety profile including a 27.3% cytokine release syndrome incidence.
  • Led by Professor Yuqin SONG of Beijing Cancer Hospital, the randomized, open-label, multicenter study plans to enroll 282 subjects with overall survival as the primary endpoint.
  • Headquartered in Shanghai, Junshi Biosciences employs more than 3,000 people globally and maintains an extensive portfolio including toripalimab, approved in over 50 countries and regions.
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Junshi Biosciences Announces Completion of First Patient Dosing in the Phase 3 Clinical Trial of JS203 in Combination with Chemotherapy for the Treatment of Diffuse Large B-cell Lymphoma

SHANGHAI, China, Oct. 23, 2026 (GLOBE NEWSWIRE) -- Shanghai Junshi Biosciences Co., Ltd (“Junshi Biosciences,” HKEX: 1877; SSE: 688180), a leading innovation-driven biopharmaceutical company dedicated to the discovery, development, and commercialization of novel therapies, announced that the first patient dosing…

·Welland, Canada
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The Hamilton Spectator broke the news in Hamilton, Canada on Friday, October 23, 2026.
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