IU Researchers Identify Clotting Protein as Potential Target in Pancreatic Cancer

IU Researchers Identify Clotting Protein as Potential Target in Pancreatic Cancer

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer.  The research, recently published in Gastroenterology and led by Melissa L. Fishel, PhD, shows that reducing fibrinogen in mouse models shrinks primary pancreatic ductal adenocarcinoma (PDAC) tumors and reduces their ability to metastasize to the liver.

Blood clot protein may help pancreatic cancer grow, new study finds

Pancreatic cancer is one of the most aggressive and deadly forms of cancer. It is often diagnosed at a late stage, when the disease has already spread to other organs such as the liver. Because of this, survival rates remain low, and scientists around the world are searching for new ways to slow the disease […] The post Blood clot protein may help pancreatic cancer grow, new study finds appeared first on Knowridge Science Report.

IU Researchers Discover Clotting Protein as Promising Therapeutic Target in

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have unveiled groundbreaking insights into the role of clotting proteins in pancreatic cancer progression. Their study, recently published in the prestigious journal Gastroenterology, reveals that targeting fibrinogen, a liver-produced clotting protein, can significantly impede the growth and metastatic potential of pancreatic ductal adenocarcinoma […]