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Ipsen to acquire ImCheck Therapeutics, expanding its leadership in oncology, strengthening its pipeline - Ipsen (OTC:IPSEY)

Ipsen will pay 350 million euros upfront for ImCheck, advancing ICT01 immunotherapy that doubled response rates in AML patients ineligible for intensive chemotherapy, data show.

  • Ipsen will acquire all shares of ImCheck Therapeutics for 350 million euros plus up to 1 billion euros in contingent payments, CEO David Loew said the deal presents an opportunity to deliver `transformative therapies`.
  • The deal centers on ICT01, targeting first-line AML patients ineligible for intensive chemotherapy, and Ipsen said it will accelerate ICT01 toward registrational studies and commercialization.
  • Clinical evidence presented at ASCO indicates EVICTION trial data in 45 patients shows ICT01 in combination with Ven-Aza achieved high responses and was well tolerated.
  • The transaction is expected to close by the end of Q1, subject to customary closing conditions and regulatory approvals; Centerview Partners advised ImCheck and Allen & Overy Shearman served as legal counsel to Ipsen.
  • Ipsen warned that development and commercial outcomes remain uncertain, despite ICT01 receiving Orphan Drug designations from the U.S. Food and Drug Administration and European Medicines Agency.
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17 Articles

Lean Left

The Phocean start-up, specializing in immuno-oncology, passes into the Ipsen giron for a minimum amount of 350 million euros, up to 1 billion. Issue: a promising treatment in development against a form of leukemia.

·Paris, France
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Lean Right

This acquisition involves a developing monoconal antibody in the front-line treatment of acute myeloid leukaemia in patients who cannot tolerate intensive chemotherapy.

·Paris, France
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The Hamilton Spectator broke the news in Hamilton, Canada on Wednesday, October 22, 2025.
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